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Thrombin

thrombin

(Science: enzyme) protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at arg gly.

Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor _ phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion.


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Connection between opioid receptors and fatty acid receptors

... this gets in right topic. I used BLAST comparisons semi randomly and found that opioid receptors were at least 20% identical with cannabinoid, thrombin and fatty acid receptors. I don't know if that is new discovery or not. BLAST program can find connections that humans may have not noticed. ...

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by mhein
Tue Jul 10, 2012 2:00 pm
 
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Topic: Connection between opioid receptors and fatty acid receptors
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thrombin cleavage

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by higherme
Thu Apr 03, 2008 10:53 pm
 
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Topic: thrombin cleavage
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by blcr11
Thu Sep 06, 2007 1:17 am
 
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ENZYME CASCADE

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by Jammerz
Tue Apr 24, 2007 4:48 am
 
Forum: Cell Biology
Topic: ENZYME CASCADE
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pls help- URGENT!!!

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by unscientific
Tue Mar 06, 2007 2:06 pm
 
Forum: Human Biology
Topic: pls help- URGENT!!!
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