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Dictionary » T » Termination codon

Termination codon

termination codon

(Science: molecular biology) The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis.

They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in e. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single gTP requiring factor, eRF.

See: ochre suppressor, amber suppressor.


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Are STOP codons involved in both TRANSCRIPTION & TRANSLATION

1)Ok, I am really confused about this. Is a "stop codon" used in both transcription and translation. I have two textbooks one says: "Three of these 64 codons are stop codons that specify the termination of a polypeptide; all the rest code for amino acids" From this ...

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by reyrey389
Sun Nov 06, 2011 8:02 am
 
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Topic: Are STOP codons involved in both TRANSCRIPTION & TRANSLATION
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Re: Determining mRNA sequences

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by id10t
Thu Mar 03, 2011 8:04 am
 
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Topic: Determining mRNA sequences
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Frameshift Question

... translation. I know that an deletion can result in a premature stop codon, but shouldn't the termination area of the template DNA still be largely unaffected? Can anybody explain?

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by billymaize
Sat Feb 06, 2010 7:40 pm
 
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Splice modification in mouse brains

... mouse is a model of Duchenne muscular dystrophy, carrying a premature termination codon in exon 23 of dystrophin. Morpholino oligos targeting dystrophin exon 23 were delivered ...

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by jonmoulton
Tue Oct 21, 2008 2:59 pm
 
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by vicereine
Thu Jun 26, 2008 7:44 pm
 
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