Dictionary » T » Termination codon

Termination codon

termination codon

(Science: molecular biology) The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis.

They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in e. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single gTP requiring factor, eRF.

See: ochre suppressor, amber suppressor.

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Are STOP codons involved in both TRANSCRIPTION & TRANSLATION

1)Ok, I am really confused about this. Is a "stop codon" used in both transcription and translation. I have two textbooks one says: "Three of these 64 codons are stop codons that specify the termination of a polypeptide; all the rest code for amino acids" From this ...

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by reyrey389
Sun Nov 06, 2011 8:02 am
Forum: Cell Biology
Topic: Are STOP codons involved in both TRANSCRIPTION & TRANSLATION
Replies: 1
Views: 4837

Re: Determining mRNA sequences

Well the article is about nonsense mediated decay and how the pre-termination codon recognition is mediated by a competition between 3' UTR associated factors that stimulate ...

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by id10t
Thu Mar 03, 2011 8:04 am
Forum: Molecular Biology
Topic: Determining mRNA sequences
Replies: 2
Views: 2120

Frameshift Question

... translation. I know that an deletion can result in a premature stop codon, but shouldn't the termination area of the template DNA still be largely unaffected? Can anybody explain?

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by billymaize
Sat Feb 06, 2010 7:40 pm
Forum: Molecular Biology
Topic: Frameshift Question
Replies: 2
Views: 1386

Splice modification in mouse brains

... mouse is a model of Duchenne muscular dystrophy, carrying a premature termination codon in exon 23 of dystrophin. Morpholino oligos targeting dystrophin exon 23 were delivered ...

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by jonmoulton
Tue Oct 21, 2008 2:59 pm
Forum: Molecular Biology
Topic: Splice modification in mouse brains
Replies: 0
Views: 1698

question about mRNA

... from an mRNA strand after translation is called a(n)_________. a) codon b) anti-codon c) termination codon d) exon e) intron ok if it said transcription I know it would be the introns ...

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by vicereine
Thu Jun 26, 2008 7:44 pm
Forum: Genetics
Topic: question about mRNA
Replies: 1
Views: 2267
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