Dictionary » T » Teratogenic



(Science: pharmacology, obstetrics) Tending to produce anomalies of formation or teratism (= anomaly of formation or development: condition of a monster).

See: teratogenicity

Origin: Gr. Gennan = to produce

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Re: Problems with gene knockdown

... of mRNA or to modify splicing of pre-mRNA. They are commonly used in zebrafish embryology, where the off-target gene modulation of siRNA is teratogenic. With a delivery moiety added to the oligo, a Vivo-Morpholino can be injected into an adult mouse, move from the blood to tissues and into ...

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by jonmoulton
Mon Sep 14, 2009 7:45 pm
Forum: Molecular Biology
Topic: Problems with gene knockdown
Replies: 1
Views: 3540

why only L-amino acids?

... the 1950s and 60s. A drug given to pregnant women for morning sickness, but it was a racemic mixture and they didn't know that one enantiomer was teratogenic (causing physical defects during birth). So a lot of childen were born with birth defects. :( http://en.wikipedia.org/wiki/Thalidomide Hope ...

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by Chris4
Sat Aug 20, 2005 8:47 pm
Forum: Molecular Biology
Topic: why only L-amino acids?
Replies: 3
Views: 10483

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