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Tau protein

Tau protein

(Science: cell biology) protein (60-70 kD) that co purifies with tubulin through cycles of assembly and disassembly and the first microtubule associated protein to be characterised. Tau proteins are a family made by alternative splicing of a single gene. It has tandem repeats of a tubulin binding domain and promotes tubulin assembly. Although tau proteins are found in all cells they are major components of neurons where they are predominantly associated with microtubules of the axon.

See: mAPs.


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Re: Why Alzheimer's happen?

... it is not related to just one gene. Some of the factors are MAPs like Tau proteins, APP (amyloid precursor protein), secretases, APOE 4 and high levels of cholosterol.

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by Parisa
Fri Jul 27, 2012 10:00 pm
 
Forum: Human Biology
Topic: Why Alzheimer's happen?
Replies: 4
Views: 3751

Amyloid beta (A4) precursor protein degradation products

Amyloid beta (A4) precursor protein degradation products of the pathogenic role of Alzheimer's disease research ... including through the inhibition of proteasome activity and the promotion of tau protein aggregation in the mitochondria progressive aggregation inhibition of the ...

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by Anonymous
Tue Jun 12, 2012 3:11 am
 
Forum: General Discussion
Topic: Amyloid beta (A4) precursor protein degradation products
Replies: 1
Views: 6463

Proteins in Mitosos and the Cell Cycle :)

APC/C and SCF are the ubiquitin-protein ligases for the cell cycle. They themselves are not phosphorylated though. ... some of the MAPs to control the cell cycle. Some examples of MAPs is Tau, MAP2, +TIPs, and Stathmin.

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by kolean
Mon Nov 30, 2009 3:10 pm
 
Forum: Cell Biology
Topic: Proteins in Mitosos and the Cell Cycle :)
Replies: 4
Views: 3105

IBO 2003 questions- please help me out

... at Expasy http://www.expasy.org/tools/ called ConSurf http://consurf.tau.ac.il/ whose job was "Projection of evolutionary conservation scores of residues on protein structures " running polymerase and histone H1 (the DNA linker in nucleosome ...

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by tittu
Wed May 14, 2008 3:14 am
 
Forum: Cell Biology
Topic: IBO 2003 questions- please help me out
Replies: 9
Views: 9437


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