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Targeting signal

Definition

noun

(molecular biology) Alternative for signal sequence, which is a chain of amino acid residues that helps direct the growing protein to its destination within the cell, e.g. to the endoplasmic reticulum (for secretion) or to the plasma membrane (to become a protein component)


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Cell membrane targeting signals.

Hey guys, first post here :) So, at the moment I'm going over the signalling of newly synthesised proteins and my lecturer's notes are confusing me a little. How are proteins destined for the cell membrane targeted? Are they synthesised by the Rough ER and ...

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by Xyroe
Sat May 08, 2010 9:31 pm
 
Forum: Cell Biology
Topic: Cell membrane targeting signals.
Replies: 3
Views: 6395

The Fiber Disease

... the human influance on the environment is completely dependant upon the signal of the earth for all actions... and to rationlize the disgrace of ... you spoke of? http://peir.path.uab.edu/pathgrad/publications/krasnykh_targeting.pdf Adenoviruses (Ads) are a family of over 50 viral mammalian ...

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by Nadas Moksha
Fri Dec 15, 2006 1:23 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479564

The Fiber Disease

... be composed of modified oligonucleotides (e.g. for improved stability, targeting, etc.) and should be delivered to cells which express polypeptides ... and albumin increases the halflife time in vivo. Nuclear localization signals fused to the polypeptides of the present invention can target the ...

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by Nadas Moksha
Sat Oct 07, 2006 3:47 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479564

The Fiber Disease

... United States Patent Application: 0060098865 Methods and reagents for targeting organic compounds to selected cellular locations - Patent 7045305 ... 15. The method of claim 1, wherein the probe provides a more intense signal when the probe/ligand conjugate is bound to the single chain antibody ...

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by Nadas Moksha
Wed Aug 16, 2006 3:44 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479564

The Fiber Disease

... process, and outer membrane translocation involves an extension of the signal peptide-dependent pathway for translocation across the cytoplasmic ... in the mRNA sequence of the secretion substrate. The translation and targeting of the substrate to the secretion loci can be coupled by the mRNA ...

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by Skytroll
Tue May 02, 2006 4:47 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479564


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