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Targeting

targeting

The process of having proteins contain certain signals such that the proteins are directed specifically towards certain cellular locations, e.g., the lysosome.

Compare: processing.


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CRISPR/Cas technology

... even still, the off targets are primarily in intergenic noncoding sequence space ad exist in a homozygous state. Most people don't see much off-targeting. It took less than a year to make the mouse, generate the data and publish the paper. If you need the mouse badly, you may choose to outsource ...

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by animodel123
Wed Mar 18, 2015 6:39 am
 
Forum: Genetics
Topic: CRISPR/Cas technology
Replies: 1
Views: 241

Re: Any ideas for vaccine development or anti-viral drugs???

... strategy for interfering with EBOV infection using antisense phosphorodiamidate morpholino oligomers (PMOs). A combination of EBOV-specific PMOs targeting sequences of viral mRNAs for the viral proteins (VPs) VP24, VP35, and RNA polymerase L protected rodents in both pre- and post-exposure therapeutic ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12592

Re: Locus specificity and ERVs - Q from a creationist

... locations in order to perform their functions. Unless we are talking about LTR promoters of native genes, this does seem to be the case. Re. locus targeting, see http://erv-faq-for-creationists.wikispaces.com/Don%27t+retroviruses+target+particular+locations+in+the+DNA%3F+Doesn%27t+this+explain+corresponding+ERVs%3F

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by BarryDesborough
Sat Aug 30, 2014 8:00 am
 
Forum: Genetics
Topic: Locus specificity and ERVs - Q from a creationist
Replies: 5
Views: 4322

My “Eureka” moment. A cure for cancer.

... by the body's control mechanisms and sometimes even artificially by pharmaceutical drugs Growth factor mechanisms would be suitable targets for targeting by the type H drugs. So for example, typical normal cells will wait for the appropriate growth factor to attach itself to the corresponding ...

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by PeterDow
Fri Oct 25, 2013 12:14 am
 
Forum: Human Biology
Topic: My “Eureka” moment. A cure for cancer.
Replies: 9
Views: 19590

Re: Gene targeting

by gauthum
Sat Jul 27, 2013 5:06 pm
 
Forum: General Discussion
Topic: Gene targeting
Replies: 17
Views: 10008
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