(Science: chemical) A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of alzheimer's disease and other central nervous system disorders.

Pharmacological action: cholinesterase inhibitor, nootropic agents, parasympathomimetic.

Chemical name: 9-Acridinamine, 1,2,3,4-tetrahydro-

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