Dictionary » T » T lymphocyte

T lymphocyte

T-lymphocyte

(Science: haematology, immunology) A class of lymphocytes, derived from the thymus gland. They originate from lymphoid stem cells that migrate from the bone marrow to the thymus and differentiate under the influence of the thymic hormones. Various subpopulations have been described.

They help to control cell-mediated immunity and the control of b-cell development, to facilitate antibody production. T lymphocytes assist in the recognition and rejection of foreign tissues and provide immune surveillance for cancer.

They express t-cell antigen receptors (cD3) and lack fc or C3b receptors. Major t-cell subsets are cD4 (mainly helper cells) and cD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to t-cell leukaemia/lymphoma.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Composition of white blood cells.

... Remember, though, that leukocyte counts vary quite a bit between individuals, and also in one individual between different time points. My own lymphocyte count is usually higher than neutrophil, though this is quite rare in humans in general. Usually neutrophils are the most numerous, followed ...

See entire post
by biohazard
Mon May 18, 2009 6:35 am
 
Forum: Cell Biology
Topic: Composition of white blood cells.
Replies: 2
Views: 235

Lymphocyte Overnight Culture parameters

You do not need to trypsinize lymphocyte cultures, they grow in suspension and do not attach to the bottom of the well. Some cells, such as monocytes do so, so if you use PBMCs to start your cultures, some cells may attach to the well, but ...

See entire post
by biohazard
Fri May 01, 2009 7:08 pm
 
Forum: Molecular Biology
Topic: Lymphocyte Overnight Culture parameters
Replies: 5
Views: 831

Re: Lymphocyte Overnight Culture parameters

Im collecting human blood samples and isolating lymphocytes using Ficoll-Hypaque method. I am trying to culture the cells and treat them to various oxidation reactions. I am having trouble with the cell culture, there does not seem to be any control over the cell cultures, for instance i plate 500,0...

See entire post
by grdnfs20
Thu Apr 30, 2009 10:25 pm
 
Forum: Molecular Biology
Topic: Lymphocyte Overnight Culture parameters
Replies: 5
Views: 831

Re:

... clarify so the differentiation into subsets can be done in several peripheral tissues including at the site of infection? Yes, the final stages of lymphocyte differentiation take place in the peripheral tissues. Often this peripheral tissue is a secondary lymphoid tissue, such as a lymph node, ...

See entire post
by biohazard
Wed Apr 15, 2009 6:35 am
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 12
Views: 789

Secondary level question-lymphocyte vs phagocyte

i am a secondary student and i confused about the difference between lymphocyte and phagocyte, as the textbook mention very little about it. Sorry for asking such simple question here... I know that phagocyte is for the phagocytosis. But i dunno what lymphocyte ...

See entire post
by lsc04361
Wed Mar 25, 2009 9:49 am
 
Forum: Human Biology
Topic: Secondary level question-lymphocyte vs phagocyte
Replies: 0
Views: 266
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 11,591 times. 
What links here | Related changes | Permanent link