Dictionary » T » T antigen

T antigen

T antigen

(Science: molecular biology) proteins coded by viral genes that are expressed early in the replication cycle of papovaviruses such as sV40 and polyoma. Essential for normal viral replication, they are also expressed in nonpermissive cells transformed by these viruses.

Originally detected as tumour antigens by immunofluorescence with antisera from tumour bearing animals. SV40 has two, large T and small t, polyoma has three, large, middle and small. Appear to be collectively responsible for transformation by these viruses. Antigens that can be found in the presence of a cancer inducing virus (an oncogene).


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Anti idiotype antibody

If i raise an antibody in a particular strain of mouse (BALB/c) with an antigen, the i collect that antibody ( monoclonal) and inject it into another BALB/c mouse. Would i get anti-idiotype, isotype or allotype antibody in mouse 2?

See entire post
by Microbuddy
Wed Feb 18, 2015 6:15 pm
 
Forum: Cell Biology
Topic: Anti idiotype antibody
Replies: 1
Views: 212

Re: immunoglobulins

... Each immunoglobulin molecule consists of four polypeptide chains: two heavy chains (H chains) and two light chains (L chains). There are five antigenically different kinds of H chains, and this difference is the basis for the classification of immunoglobulins. The five major classes of immunoglobulins ...

See entire post
by RZachary1
Wed Jan 14, 2015 5:49 am
 
Forum: Cell Biology
Topic: immunoglobulins
Replies: 2
Views: 2188

I have got some BIG issues! forgive the long post

... . Blood Group Systems : What the heck are MNSs? I have a little understanding of Rh and how terrible it can be if mommys blood detect different antigen in Baby's blood however I don't get the genes Dd, Cc and Ee genes associated with it. Also tones of jargons! I will actually paste the whole ...

See entire post
by saddy51
Sun Jan 04, 2015 10:39 am
 
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1783

An Investigation of ABO Group Antigen Structure question?

Group O red blood cells have been incubated with either UDP-galactose or UDP-N- acetyl galactosamine together with group A, group B or group O serum for six hours at 37oC as follows: Tube 1 Group O cells UDP-NacG O-serum Tube 2 Group O cells UDP-Gal O-serum Tube 3 Group O cells UDP-NacG B-serum Tube...

See entire post
by revision
Fri Feb 07, 2014 8:17 pm
 
Forum: Molecular Biology
Topic: An Investigation of ABO Group Antigen Structure question?
Replies: 1
Views: 2817

Blood Genetics help please

The A, B and O antigens of the human blood system are sugars that can be found on the surface of red blood cells. The alleles A, B and O refer to the variant forms of the proteins (enzymes) that produce the sugar antigens. The O ...

See entire post
by girlslovebarbie
Sat Feb 01, 2014 2:58 pm
 
Forum: Genetics
Topic: Blood Genetics help please
Replies: 2
Views: 4034
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 13,330 times. 
What links here | Related changes | Permanent link