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TDF gene



An abbreviation for testis-determining factor gene, a gene that codes for testis-determining factor in certain animals.


Since the presence of Y chromosome in humans indicates maleness, scientists thought that the gene responsible for the determination of maleness in humans must have been located in the Y chromosome. Later, the SRY gene was found. Scientists then believed that this is the testis-determining factor gene since it was found to trigger the pathway that leads to the development of embryo to become male. However, they also pointed out that this gene is not the only gene responsible for sexual development and determination.

Synonym: SRY gene

See also: sex chromosome, TDF protein

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The violent hormone?

... have it) leads to a more agressive behaviour among other things... The genetic ground that it stands on are the genes on the Y chromosome. As you ... of testicles as to nature's default ovaries, where the named it from TDF. Or something like that.... :lol: Regards,

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by MrMistery
Wed Aug 17, 2005 6:49 pm
Forum: Human Biology
Topic: The violent hormone?
Replies: 13
Views: 7003

y chromosome disorders

Up to now, only few Y-linked genes has been identified (holandric genes): 1. resesive gene "wt", causing membranes ... condition. 4. genes controlling spermatogenesis 5. testis determining factor (TDF) 6. H-Y antigen 7. some genes for height

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by Dr.Stein
Fri Jul 29, 2005 9:31 am
Forum: Genetics
Topic: y chromosome disorders
Replies: 5
Views: 8446

Traits Question

... Describes a trait or disorder requiring the presence of two copies of a gene mutation at a particular locus in order to express observable phenotype; ... * IL3RAY (interleukin-3 receptor), * SRY (sex-determining region), * TDF (testis determining factor), * ZFY (zinc finger protein), PRKY (protein ...

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by b_d_41501
Thu Jun 02, 2005 9:38 pm
Forum: Genetics
Topic: Traits Question
Replies: 10
Views: 8069

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