Dictionary » S » Surrogate endpoint

Surrogate endpoint

Definition

noun

A measure of the effect of a treatment to indicate, reflect or substitute a clinical endpoint.


Supplement

In clinical or laboratory experiments, surrogate endpoints are used when a clinical endpoint is undesired or unethical to wait for (e.g. death) or when there are limited number of cases that a statistical test cannot be applied.

An example is CD4 cell counts as a surrogate marker for death from HIV infection.


Also called: surrogate marker

See also: clinical endpoint


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified 01:34, 29 August 2009. This page has been accessed 1,116 times. 
What links here | Related changes | Permanent link