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Subunit

Definition

noun, plural: subunits

(general) A subdivision or a distinct component of a larger unit


Supplement

The word subunit when used in general sense pertains to a particular part of a larger unit. In structural biology, subunit may pertain to biochemical molecules comprised of distinct components. For instance, protein subunit pertains to a protein molecule that can assemble with another protein molecule to form a complex. Myosin, for example, is comprised of six subunits. Microtubules, which are tubular polymers of the cytoskeleton in the cytoplasm, are each built of tubulin subunits. Proteins that have a relatively small number of subunits are sometimes described as oligomeric. Those that have a large number of subunits are described as multimeric. Protein subunits may also be classified as regulatory subunit or catalytic subunit depending on the primary function that they serve. There are however certain complexes that have both regulatory and catalytic subunits and are termed holoenzymes.


Word origin: sub-, (meaning under) from Latin preposition sub under (close to, up to, towards) + unit

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principle of error-prone PCR???

... the size of Mn ions affect the Taq enzyme? Did they changes the fourth-level structure of the Taq enzyme, such as combine with the regulatory subunit to control the activity, or something else. I mean, it is obviously not the charges, Mn2+ ions carry two positive as well as magesium; plus, ...

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by feixiaorou
Wed Oct 01, 2014 3:51 am
 
Forum: Molecular Biology
Topic: principle of error-prone PCR???
Replies: 4
Views: 1258

Re: Any ideas for vaccine development or anti-viral drugs???

... 2006 Mar;50(3):984-93. Phosphorodiamidate morpholino oligomers (PMO) are a class of uncharged single-stranded DNA analogs modified such that each subunit includes a phosphorodiamidate linkage and morpholine ring. PMO antisense agents have been reported to effectively interfere with the replication ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 5163

peptidyl transferase

Hey there. I have a little problem. :( PTC is an enzyme which catalyzes the peptide formation reaction. It is located in 60s subunit of ribosome. EC 2.3.2.12 . I actually need a pdb file of ptc for my docking issue. how can I find it??

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by Parisa
Tue Nov 05, 2013 10:11 pm
 
Forum: Cell Biology
Topic: peptidyl transferase
Replies: 2
Views: 1493

peptidyl transferase center?!

Hey there. I have a little problem. :( PTC is an enzyme which catalyzes the peptide formation reaction. It is located in 60s subunit of ribosome. EC 2.3.2.12 . there are some pdb IDs like 3j3b n 3j3f but not for the pure protein. I actually need a pdb file of ptc for my docking issue. ...

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by Parisa
Tue Nov 05, 2013 12:12 am
 
Forum: Bioinformatics
Topic: peptidyl transferase center?!
Replies: 1
Views: 1540

cellular mechanisms that result in symptoms of cholera

The cholera toxin (CTX or CT) is an oligomeric complex made up of six protein subunits: a single copy of the A subunit (part A), and five copies of the B subunit (part B), connected by a disulfide bond. The five B subunits form a five-membered ring that binds to ...

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by adithya528
Tue Dec 11, 2012 1:49 pm
 
Forum: Cell Biology
Topic: cellular mechanisms that result in symptoms of cholera
Replies: 4
Views: 6127
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