Dictionary » S » Substrate

Substrate

Definition

noun, plural: substrates

(geology)

A substratum or an underlying stratum.

(chemistry)

The substance acted upon by an enzyme.

(biology)

The earthy material in which an organism lives, or the surface or medium on which an organism grows or is attached.

(marine biology)

The material (e.g. dirt, rocks, sand, gravel) in the bottom of a marine habitat, or one that forms the bed of a stream (or of an aquarium); the source of food for some microorganisms.


Supplement

Word origin: L. Stratum = layer.

Related terms: substrate inhibition, substrate-level phosphorylation, substrate specificity, suicide substrate, enzyme-substrate complex.

Synonym: substratum.


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I have got some BIG issues! forgive the long post

... gene at the ABO locus, catalyze the last step of the synthesis, while the protein coded by the O allele is non-functional; therefore, the acceptor substrate, (H antigen) remains without a further modification. GENETIC PATHWAY OF THE ABO SYSTEM The term secretor, as used in blood banking, refers ...

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by saddy51
Sun Jan 04, 2015 10:39 am
 
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1906

Exp. antisense treatment for Pompe disease

... of antisense as a potential therapeutic. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease. Clayton NP, Nelson CA, Weeden T, Taylor KM, Moreland RJ, Scheule RK, Phillips L, Leger AJ, Cheng SH, Wentworth ...

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by jonmoulton
Wed Oct 29, 2014 3:58 pm
 
Forum: Genetics
Topic: Exp. antisense treatment for Pompe disease
Replies: 0
Views: 531

Re:

... which is I used for prevent any contamination in the reaction but I think there is no difference after added this reagent, means that OD blank and substrate control still higher.

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by intandiana
Sun Jan 19, 2014 5:59 am
 
Forum: Molecular Biology
Topic: blank and substrate control give OD reads
Replies: 9
Views: 6574

Re: blank and substrate control give OD reads

You centrifuge the reactions in the 96-well plate and then in that you measure absorbance? How can you do that if the bottom is blocked by your substrate? Can you describe your reactions and controls in more detail including some example absorbances so we can make better idea what you have in ...

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by intandiana
Sun Jan 19, 2014 5:57 am
 
Forum: Molecular Biology
Topic: blank and substrate control give OD reads
Replies: 9
Views: 6574

Re: blank and substrate control give OD reads

Here's another approach. Set up a pair of tubes identically, containing everything but the xylanase. Check their OD. Add xylanase to one of the tubes and mix. Check the OD again. That way you control for other potential errors, such as a difference in buffer concentration or a variation in tube thi...

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by intandiana
Sun Jan 19, 2014 5:45 am
 
Forum: Molecular Biology
Topic: blank and substrate control give OD reads
Replies: 9
Views: 6574
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