Substitution mutation

Definition

A type of point mutation in which a single nucleotide is substituted with (or exchanged for) a different nucleotide that may result in an altered sequence of amino acid during translation, which may render the newly synthesized protein ineffective.


Supplement

Examples of base-pair substitutions: purine substituted with a different purine (A → G) or a pyrimidine for a different pyrimidine (C → T). This type of substitution mutation is transition. Another kind is transversion, which is less common. In transversion, purine is substituted with pyrimidine or a pyrimidine with a purine.


See also: point mutation.

Retrieved from "http://www.biology-online.org/bodict/index.php?title=Substitution_mutation&oldid=94807"
First | Previous (Substitution) | Next (Substitution product) | Last
Please contribute to this project, if you have more information about this term feel free to edit this page.