group of haemolytic exotoxins released by streptococci. _ haemolysin: 26-39 kd (four types), forms ring like structures in membranes (see streptolysin O). Lipid target unclear. _ haemolysin: a hot cold haemolysin with sphingomyelinase C activity. _ haemolysin: complex of two proteins (29 and 26 kD) that act synergistically, rabbit erythrocytes particularly sensitive. _ toxin: heat stable peptide (5 kD) with high proportion of hydrophobic amino acids. Seems to act in a detergent like manner (c.f. Subtilysin), but may form hydrophilic transmembrane pores by cooperative interaction with other _ toxin molecules. Leucocidin (panton valentine leucocidin): two components f (fast migration on CM cellulose column: 32 kD) and s (slow: 38 kD). Mode of action contentious.
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... when treated with Valacyclovir an antiviral drug for 8 weeks. Streptococcal infections have been followed in some children by the abrupt ... and releasing massive amounts of waste products, enteric poisons, and toxins which disable brain metabolism. Mature tapeworms can lay a million ...
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