Dictionary » S » Stop codons

Stop codons

stop codon --> termination codon

(Science: molecular biology) The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis.

They are not represented by any tRNA and termination is catalysed by protein release factors. There are two release factors in e. Coli, RF1 recognises UAA and UAG, RF2 recognises UAA and UGA. Eukaryotes have a single gTP requiring factor, eRF.

See: ochre suppressor, amber suppressor.


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Can I deduce the Number of Proteins Produced?

... From this you get the average number of nucleotides (do not forget the STOP codons). And since you know, that 80% of 9.7 x 10^6 base pares codes for proteins, it should ...

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by JackBean
Fri Jun 29, 2012 7:11 am
 
Forum: Genetics
Topic: Can I deduce the Number of Proteins Produced?
Replies: 1
Views: 1919

Molecular gene (genome) concept scientifically untenable

... but they usually contain obvious disablements such as frameshifts or stop codons in the middle of coding domains. This prevents them from producing a functional product ...

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by PAWahid
Wed May 02, 2012 4:54 am
 
Forum: Molecular Biology
Topic: Molecular gene (genome) concept scientifically untenable
Replies: 12
Views: 20733

Wobble hypothesis.How does met & trp not get mis translated?

You seem to have a misunderstanding about this. Among the 64 possible codons, 61 codons specify amino acids (except the 3 stop codons). If each tRNA molecule pairs with its complementary codon using Watson-Crick base ...

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by Sue4
Tue Apr 10, 2012 4:30 pm
 
Forum: Molecular Biology
Topic: Wobble hypothesis.How does met & trp not get mis translated?
Replies: 2
Views: 4353

I need some actual DNA sequences for a computer program.

... If the random sequence is AUGAAAGGUAG (with AUG = Start and UAG = Stop) the 'gene' = AAAGG. Which is 5 bases = 2/3 codons. Where as an actually DNA sequence will tend to have genes of multiples of 3 unless ...

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by Awol
Fri Mar 30, 2012 3:58 pm
 
Forum: Molecular Biology
Topic: I need some actual DNA sequences for a computer program.
Replies: 7
Views: 2319

I need some actual DNA sequences for a computer program.

Well, he program should read only in-frame start and stop codons.

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by JackBean
Fri Mar 30, 2012 3:37 pm
 
Forum: Molecular Biology
Topic: I need some actual DNA sequences for a computer program.
Replies: 7
Views: 2319
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