Steroid 11 beta-monooxygenase

steroid 11 beta-monooxygenase

(Science: enzyme) A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an nADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital).

Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)

Registry number: EC 1.14.15.4


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