Staging of breast cancer is based on the tNM Classification which classifies the size, site and spread of the disease.Therapeutic decisions are formulated in part according to staging (they are formulated primarily according to lymph node status and ER and pR receptor levels in the tumourous tissue, refer definition of ER and PR in this dictionary). The numbers I, II, III and iV are used to denote the stages and each number refers to a possible combination of tNM factors. For example: a Stage I breast cancer is defined by the TMN group: t1, n0, M0 which mean:T1 - tumour is 2cm or less in diameter, N0 - no regional lymph node metastasis, M0 - No distant metastasis. A complete outline of TMN and Staging is available from pDQ, for which refer to the resource centre's listing of information services.

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