Dictionary » S » Split gene

Split gene



A gene that when transcribed results in pre-mRNA containing exons interrupted by introns


Split genes are first observed in eukaryotes. No split genes are reported yet in prokaryotes. Prokaryotic genes are contiguous. Eukaryotic genes, in contrast, contain segments of DNA that are expressed (called exons) interrupted by segments that are not expressed (called introns). During gene expression, the resulting mRNA contains both exons and introns. It then undergoes splicing by which introns are removed so that it would only contain exon sequences before it is transported to the cytoplasm.


Please contribute to this project, if you have more information about this term feel free to edit this page

Results from our forum

Re: Brain size=IQ level theory (Blacks vs Whites & Asians)

... it's obvious your "doctorate" is neither in anthropology nor genetics. You simply don't know what you're talking about. In terms of evolutionary ... at Homo sapiens and Neanderthals we see the beginnings of a genetic split about a half million years ago after at least 1 million years ...

See entire post
by Seth90210
Sun Feb 16, 2014 9:35 pm
Forum: Human Biology
Topic: Brain size=IQ level theory (Blacks vs Whites & Asians)
Replies: 75
Views: 332638

Living or not? (viruses,viroids and prions).

... by the first discovery of an extremely large virus. Viruses are generally stripped down, efficient predators, only carrying as much DNA or ... the viruses seem to have had a common ancestor with eukaryotes, but it split off right after the eukaryotes diverged from bacteria and archaea. ...

See entire post
by Sumanth001
Sun Dec 08, 2013 12:37 pm
Forum: Microbiology
Topic: Living or not? (viruses,viroids and prions).
Replies: 15
Views: 17997

Genetics with Mitosis and Meiosis

... I got anything wrong. Anaphase (in any type of division) is after the genetic material has separated and is being pulled toward the ends of the ... II is basically like mitosis in that sister chromatids are being split apart, but there are half as many chromosomes (one from each homologous ...

See entire post
by wildfunguy
Sun Feb 03, 2013 11:45 pm
Forum: Genetics
Topic: Genetics with Mitosis and Meiosis
Replies: 2
Views: 9248


... there is some small alternative-intron in your exon, which can be thus split why are you using primers only for one exon at a time? Is your aim ... 4 sets of primers. I was going to amplify 4 overlapping regions of the gene, run them on a gel, cut out the bands of expected size, purify them, ...

See entire post
by polkadotshorts
Mon Dec 10, 2012 7:12 pm
Forum: Genetics
Topic: How to clone a gene with lots of splicing intermediates?
Replies: 6
Views: 4444

Real Time reverse transcription PCR Questions

... in mind is to transfect my cells with my desired proteins and when I split my cell lysate I will keep one for protein and one to isolate RNA. ... I know this is a dumb question but I’m having trouble locating my exact gene sequence! My project is on IL6. I used NCBI to search and found IL6 ...

See entire post
by wessH
Sun Jun 03, 2012 2:21 pm
Forum: Molecular Biology
Topic: Real Time reverse transcription PCR Questions
Replies: 0
Views: 2939
View all matching forum results

This page was last modified 06:41, 29 March 2014. This page has been accessed 12,836 times. 
What links here | Related changes | Permanent link