Spasticity

... been used widely internationally and has given insight into a number of questions regarding muscle spindle function in normal and in patients with spasticity or rigidity. The method has also been used to explore a number of neural systems in healthy human volunteers, e.g. proprioceptive, tactile, ...

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... this group. The clinical picture is one of progressive weakness, long tract signs and visual and auditory deficits progressing to frank dementia, spasticity, and unresponsiveness. In most patients the disease is evident early in the first decade. The common leukodystrophies (metachromatic leukodystrophy, ...

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... may develop an early-onset type (severe form) shortly after age 2 that causes a large skull, coarse facial features, profound mental retardation , spasticity , aggressive behavior, joint stiffness and death before age 20. A late-onset type (mild form) causes later and less severe symptoms. Small ...

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