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Snares

SNAREs

receptors for sNAPs. The neuronal receptor for vesicle SNAPs, v sNARE, is synaptobrevin, also called vAMP 2. The target (t SNARE) associated with the plasma membrane of the axonal terminal is syntaxin. The SNAP SNARE complex is apparently responsible for regulating vesicle targeting: neurotoxins such as tetanus toxin and botulinum toxin selectively cleave sNAREs or SNAPs.

See: cellubrevin.


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Calcium ions

... not only; some SNARE interactions are also involved, but they are not at their full capacity). There is a protein(synaptotagmin) that binds the SNAREs and does not allow them to fully interact, thereby precluding membrane fusion. Calcium binds to synaptotagmin and causes a conformational change ...

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by MrMistery
Fri Nov 28, 2008 4:14 pm
 
Forum: Human Biology
Topic: Calcium ions
Replies: 2
Views: 870


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