Dictionary » S » Silent mutation

Silent mutation

Definition

noun, plural: silent mutations

A form of point mutation resulting in a codon that codes for the same or a different amino acid but without any functional change in the protein product.


Supplement

Silent mutations do not cause changes in the amino acid sequence and hence the protein is still functional. Because of that they are regarded as though they are evolutionarily neutral.


Compare: nonsense mutation, missense mutation
See also: point mutation


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Re: Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated ... and google "synonymous substitution mutability" and "silent substitution mutability" (without quotes) Yeah, so? How is that related?

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by JackBean
Mon Sep 10, 2012 3:08 pm
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12652

Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated ... and google "synonymous substitution mutability" and "silent substitution mutability" (without quotes)

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by Rap
Thu Sep 06, 2012 1:54 am
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 12652

DNA and Protein Synthesis

... DNA, but of the protein. Anyway, there are several options. Either the mutation will be silent, i.e. coding for the same amino acid and you will see no change in protein. Or the amino ...

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by JackBean
Tue Feb 28, 2012 8:22 am
 
Forum: Genetics
Topic: DNA and Protein Synthesis
Replies: 2
Views: 5376

Confusion about Missense Mutation

Yes, agree with JackBean, missense mutation will alter the amino acid. If may not alter the amino acid, we call that silent mutation.

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by magicsiew
Sat Jul 02, 2011 12:06 pm
 
Forum: Genetics
Topic: Confusion about Missense Mutation
Replies: 2
Views: 1787

Transgenic Mutation

Not the same thing as a point mutation. You are right in that 'transgenic' means mixing of genetic information (DNA) ... into any species genome that would cause a mutated expression (though there are silent transgenic mutations too in which there is no expression).

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by kolean
Tue Feb 09, 2010 2:23 pm
 
Forum: Molecular Biology
Topic: Transgenic Mutation
Replies: 1
Views: 3094
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