Dictionary » S » Silent mutation

Silent mutation

Definition

noun, plural: silent mutations

A form of point mutation resulting in a codon that codes for the same or a different amino acid but without any functional change in the protein product.


Supplement

Silent mutations do not cause changes in the amino acid sequence and hence the protein is still functional. Because of that they are regarded as though they are evolutionarily neutral.


Compare: nonsense mutation, missense mutation
See also: point mutation


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Results from our forum


Re: Which has a greater impact of evolution, mutations or genet

... genetic recombination produces more genetic variation compared to mutations and thus is a more important source on of variability on which ... likely meant pathogenic mutations. It such cases benign mutations and silent mutations are considered normal variation resulting in alternative ...

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by Cat
Fri Oct 31, 2014 2:26 am
 
Forum: Evolution
Topic: Which has a greater impact of evolution, mutations or genet
Replies: 1
Views: 1004

Re: Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated ... and google "synonymous substitution mutability" and "silent substitution mutability" (without quotes) Yeah, so? How is that related?

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by JackBean
Mon Sep 10, 2012 3:08 pm
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 15448

Re:

Rap: DNA does not evolve into mutation-resistant. Simply if the mutation would be lethal then nothing with mutated ... and google "synonymous substitution mutability" and "silent substitution mutability" (without quotes)

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by Rap
Thu Sep 06, 2012 1:54 am
 
Forum: Evolution
Topic: Increasing Information For Genetic Algorithm
Replies: 8
Views: 15448

DNA and Protein Synthesis

... DNA, but of the protein. Anyway, there are several options. Either the mutation will be silent, i.e. coding for the same amino acid and you will see no change in protein. Or the amino ...

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by JackBean
Tue Feb 28, 2012 8:22 am
 
Forum: Genetics
Topic: DNA and Protein Synthesis
Replies: 2
Views: 7957

Confusion about Missense Mutation

Yes, agree with JackBean, missense mutation will alter the amino acid. If may not alter the amino acid, we call that silent mutation.

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by magicsiew
Sat Jul 02, 2011 12:06 pm
 
Forum: Genetics
Topic: Confusion about Missense Mutation
Replies: 2
Views: 2046
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