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signal sequence

A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum.

See: signal recognition particle.

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Trying to prove height increase...need help

... cartilage/synovial joint. When the articular cartilage is loaded it results in the release of water upon deformation and perhaps cartilagenous signals trigger processes in the epiphysis.

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by MiniGolfer
Thu Jul 24, 2014 9:09 pm
Forum: General Discussion
Topic: Trying to prove height increase...need help
Replies: 2
Views: 2557

Action potentials of an earthworm going negative first

... on the earthworm if it at all influences this is that they have 3 main nerve cords where all the nerves bundles are held, 2 of them carrying the signals down the worm and the other transmitting them to the front. Thanks very much guys. Sorry if I'm not being clear. Just ask anything if you need ...

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by IsDolan
Mon Jan 20, 2014 3:28 am
Forum: General Discussion
Topic: Action potentials of an earthworm going negative first
Replies: 2
Views: 1592

Re: Am I the Next Step in Human Evolution?

... are also others who appear old and have no body hair (though that is more rare as lack of hair is associated with youth and should not send the signals of maturity) and those with a lot of hair who look younger than they are. Example, my brother grows a very thick beard and has a lot of hair ...

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by badgertoes
Sat Dec 28, 2013 8:31 am
Forum: Evolution
Topic: Am I the Next Step in Human Evolution?
Replies: 25
Views: 45095

Living or not? (viruses,viroids and prions).

... to disable Mimivirus. Both viruses share an identical set of genes involved in transcribing their DNA into RNA, and use an identical set of signals to indicate where the transcripts should start and stop. Mimivirus also contains a number of genes used in the translation of RNA into protein. ...

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by Sumanth001
Sun Dec 08, 2013 12:37 pm
Forum: Microbiology
Topic: Living or not? (viruses,viroids and prions).
Replies: 15
Views: 18022

Cell regulation/death

... the body (e.g. making fingers on fetus), that process requires programmed cell death. The mammalian cells require growth hormones and other signals to proliferate and live. If they lack them, or they receive signal to die off, they undergo the PCD. The telomeres are problem, but they measure ...

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by JackBean
Thu Nov 28, 2013 12:32 pm
Forum: Cell Biology
Topic: Cell regulation/death
Replies: 2
Views: 2838
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