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Signal peptidase

Definition

noun, plural: signal peptidases

The enzyme that catalyzes the breaking off of the signal peptide from the growing protein


Supplement

Several signal peptidases have been found both in eukaryotes and prokaryotes. In eukaryotic cell, the signal peptidases are found at the rough endoplasmic reticulum (presumably at the luminal side), at the mitochondrion, plasma membrane, and chloroplasts. In prokaryotes, they are in the prokaryotic plasma membrane.

Examples of signal peptidases include:


See also:


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The Fiber Disease

... says Kämper. wait.... The mammalian cell constantly receives signals from its surroundings to which it has to respond appropriately. Growth ... membrane-spanning sequences, (2) signal peptides with signal peptidase (SPase) I-like cleavage sites, and (3) signal peptides with SPase ...

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Tue Nov 14, 2006 5:17 am
 
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... of the same variety. This may be an important method of regulation of peptidase activity. "The plot thickens Paradoxically, our overall picture ... from proteases via antigens; and several receptors on important signal transmission pathways are activated by proteases (see 'Signalling: ...

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