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Sialic acid

sialic acid --> neuraminic acid

(Science: chemical) Sometimes known as sialic acid, but strictly one of a family of sialic acids (which includes also N glycolyl neuraminic acid and O substituted derivatives).

It is a 9 carbon sugar formed by adding to mannose three carbons from pyruvate. Occurs in the subset of glycolipids known as gangliosides and in glycoproteins.

The presence of its carboxyl group on glycolipids and glycoproteins is responsible for much of the negative charge on animal cell surfaces.


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The Implausible Engines of Evolution

... malaria, survived it, and maintained the mutation? If this animals's sialic acid lethal, then I wonder how animals survive today with this still present in their gene. ...

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by Tomn
Tue Oct 11, 2011 10:27 pm
 
Forum: Evolution
Topic: The Implausible Engines of Evolution
Replies: 40
Views: 65546

Binding proteins to cytoplasmic surface of cellular membrane

this is what i read. From 61 to 92% of the total sialic acid is present on the cell SURFACE as measured by its susceptibility to cleavage. But its amount ...

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by havery01
Tue Nov 30, 2010 8:13 pm
 
Forum: Cell Biology
Topic: Binding proteins to cytoplasmic surface of cellular membrane
Replies: 5
Views: 4513

Re: Binding proteins to cytoplasmic surface of cellular membrane

... on page 55 that says that Lectin Pisium Sativum binds specifically to Sialic Acid. SO! The question is, does sialic acid only present itself on the outside of the cell ...

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by brantozeke
Sat Nov 27, 2010 2:56 pm
 
Forum: Cell Biology
Topic: Binding proteins to cytoplasmic surface of cellular membrane
Replies: 5
Views: 4513

Sialic acid

And by the way sialic acid is not a disease but a component of bacterial cell wall.

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by canalon
Sun Feb 15, 2009 11:05 pm
 
Forum: Microbiology
Topic: Sialic acid
Replies: 10
Views: 3806

Sialic acid

no, this is how you do it http://lmgtfy.com/?q=sialic+acid

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by mith
Fri Feb 13, 2009 9:14 pm
 
Forum: Microbiology
Topic: Sialic acid
Replies: 10
Views: 3806
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