Dictionary » S » Serine protease

Serine protease

serine protease

(Science: enzyme) One of a group of endoproteases from both animal and bacterial sources that share a common reaction mechanism based on formation of an acyl enzyme intermediate on a specific active serine residue. Serine proteases are all irreversibly inactivated by a series of organophosphorus esters, such as di isopropylfluorophosphate (dFP) and by naturally occurring inhibitors (serpins). This group includes enzymes active in digestion, blood clotting, immune reactios, and fertilization of the ovum.

Examples are trypsin, chymotrypsin and the bacterial enzyme subtilisin.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Edman Degradation Problem

... (all written with N terminus at the left and C terminus at the right) Protease I ////// Protease II NMLCST ////// STFSTNSC NST ////// STNPGPT NPGPT ... Protease I: Only between asparagine and threonine Protease II: Between Serine and cysteine, serine and threonine, and asaparagine and cysteine? ...

See entire post
by pinkerpikachu
Sun Oct 16, 2011 7:35 pm
 
Forum: Molecular Biology
Topic: Edman Degradation Problem
Replies: 1
Views: 3987

Dispersing Agents For Cell Cultures

... researchers and we students are using it. Trypsin more or less is a serine protease which is used in digesting (?), which digests certain proteins. So with respect to ...

See entire post
by FusionVisionary
Wed Mar 05, 2008 1:16 am
 
Forum: Cell Biology
Topic: Dispersing Agents For Cell Cultures
Replies: 2
Views: 2828

The Fiber Disease

... following the identification of a novel homology with the Kazal-type serine protease inhibitors. Along with the electrostatic potential and the conservation of key amino ...

See entire post
by Nadas Moksha
Mon Dec 11, 2006 8:07 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479141

bacterial cell walls and digestion by proteases

... can be achieved if we make two assumptions: 1. The organisms use a protease which recognizes “usual” L-amino acids. 2. The oligopeptide bridges ... acids present in the tetrapeptide. In addition, Glycine, Threonine, Serine and Aspartic acid can be found in interbridge. However, branched-chain ...

See entire post
by druid
Mon Nov 06, 2006 10:04 pm
 
Forum: Microbiology
Topic: bacterial cell walls and digestion by proteases
Replies: 1
Views: 3817

The Fiber Disease

... this is the case of the trialysin peptides solved by NMR and the serine protease inhibitors solved by diffraction studies. For most of the chosen targets we failed ...

See entire post
by Nadas Moksha
Mon Sep 11, 2006 1:39 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5479141
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 3,690 times. 
What links here | Related changes | Permanent link