Serine protease

serine protease

(Science: enzyme) One of a group of endoproteases from both animal and bacterial sources that share a common reaction mechanism based on formation of an acyl enzyme intermediate on a specific active serine residue. Serine proteases are all irreversibly inactivated by a series of organophosphorus esters, such as di isopropylfluorophosphate (dFP) and by naturally occurring inhibitors (serpins). This group includes enzymes active in digestion, blood clotting, immune reactios, and fertilization of the ovum.

Examples are trypsin, chymotrypsin and the bacterial enzyme subtilisin.


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified on 3 October 2005, at 21:16. This page has been accessed 4,359 times. 
What links here | Related changes | Permanent link