1. To separate from the owner for a time; to take from parties in controversy and put into the possession of an indifferent person; to seize or take possession of, as property belonging to another, and hold it till the profits have paid the demand for which it is taken, or till the owner has performed the decree of court, or clears himself of contempt; in international law, to confiscate. Formerly the goods of a defendant in chancery were, in the last resort, sequestered and detained to enforce the decrees of the court. And now the profits of a benefice are sequestered to pay the debts of ecclesiastics. (Blackstone)

2. To cause (one) to submit to the process of sequestration; to deprive (one) of one's estate, property, etc. It was his tailor and his cook, his fine fashions and his french ragouts, which sequestered him. (south)

3. To set apart; to put aside; to remove; to separate from other things. I had wholly sequestered my civil affairss. (bacon)

4. To cause to retire or withdraw into obscurity; to seclude; to withdraw; often used reflexively. When men most sequester themselves from action. (hooker) A love and desire to sequester a man's self for a higher conversation. (bacon) 5. (Chem) To bind, so as to make [a metal ion] unavailable in its normal form; said of chelating agents, such as eDTA, which, in a solution, bind tightly to multivalent metal cations, thereby lowering their effective concentration in solution. Compounds employed particu a48 larly for this purpose are called sequestering agents, or chelating agents. In biochemistry, sequestration is one means of reversibly inhibiting enzymes which depend on divalent metal cations (such as magnesium) for their activity. Such agents are used, for example, to help preserve blood for storage and subsequent use in transfusion.

1. Sequestration; separation.

2. A person with whom two or more contending parties deposit the subject matter of the controversy; one who mediates between two parties; a mediator; an umpire or referee.

3. (Science: medicine) same as sequestrum.

Origin: F. Sequestrer, L. Sequestrare to give up for safe keeping, from sequester a depositary or trustee in whose hands the thing contested was placed until the dispute was settled. Cf. Sequestrate.

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