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Sequence analysis

sequence analysis

A multistage process that includes the determination of a sequence (protein, carbohydrate, etc.), its fragmentation and analysis, and the interpretation of the resulting sequence information. This information is useful in that it: 1) reveals the similarities of homologous genes, thereby providing insight into the possible regulation and functions of these genes; and 2) leads to a better understanding of disease states related to genetic variation. New sequencing methodologies, fully automated instrumentation, and improvements in sequencing-related computational resources contribute to the potential for genome-size sequencing projects.


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Re: Any ideas for vaccine development or anti-viral drugs???

... translation start site region of EBOV VP35 positive-sense RNA generated sequence-specific and time- and dose-dependent inhibition of EBOV amplification ... EBOV budding has not been established. Therefore, we used VP40 deletion analysis, virus-like particle-release assays, and confocal microscopy ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 504

Free online software tools for molecular cloning

... tools facilitating your everyday cloning work. At this time a DNA sequence editor and a restriction analysis tool are available. I have also some other ideas that may evolve into additional tools ...

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by vladCH
Sat Feb 22, 2014 8:12 pm
 
Forum: Molecular Biology
Topic: Free online software tools for molecular cloning
Replies: 0
Views: 1339

Living or not? (viruses,viroids and prions).

... that could only be distinguished using electron microscopy. They also sequenced its entire genome, which turned out to be the largest virus genome ... horizontal gene transfer, although it would be good to see a similar analysis for a lot more of the shared genes. What they don't do, however, ...

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by Sumanth001
Sun Dec 08, 2013 12:37 pm
 
Forum: Microbiology
Topic: Living or not? (viruses,viroids and prions).
Replies: 15
Views: 11290

Re: Gene targeting

These come to mind. genetics organic chemistry (chemistry major's year sequence) biochemistry (chemistry major's year sequence) microbiology cell ... molecular genetics plant physiology evolution instrumental chemical analysis statistics bioinformatics programming (for instance, C++ or a similar ...

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by jonmoulton
Thu Apr 25, 2013 6:11 pm
 
Forum: General Discussion
Topic: Gene targeting
Replies: 17
Views: 8054

cell specific markers

... which would target particular ethnic groups”. 99.9% of the genetic sequence of any two human individuals is said to be identical – but the 0.1% ... not only exist, but they do so in unexpectedly high numbers. Our analysis focussed on so called single nucleotide polymorphisms – SNPs – that ...

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by MarkHolland
Sat Mar 30, 2013 3:16 pm
 
Forum: Cell Biology
Topic: cell specific markers
Replies: 3
Views: 6286
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