Edit page | Page history | Printable version

sequence analysis

A multistage process that includes the determination of a sequence (protein, carbohydrate, etc.), its fragmentation and analysis, and the interpretation of the resulting sequence information. This information is useful in that it: 1) reveals the similarities of homologous genes, thereby providing insight into the possible regulation and functions of these genes; and 2) leads to a better understanding of disease states related to genetic variation. New sequencing methodologies, fully automated instrumentation, and improvements in sequencing-related computational resources contribute to the potential for genome-size sequencing projects.