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Selection coefficient

selection coefficient

The proportion of progeny or potential progeny not surviving to sexual maturity; usually defined artificially by expressing the fitness of a phenotype as a fraction of the mean or optimal fitness to give the relative fitness, and subtracting this fraction from unity. If the mean size of family in the population is 3.2 and that for a particular genotype is 2.4 then the fitness of the phenotype is 2.4/3.2 =0.75 and the selection coefficient =1-0.75 =.25 = 5


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mutation-selection balance

... copy of the lethal dominant disease allele into a population, natural selection eliminates it. In this case, p, the gene frequency of the lethal ... lethal in homozygotes, then q=√(μ/s), where s is again the selection coefficient for those who have a homozygous affected genotype. N.B. √ is ...

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by Monco
Mon Mar 04, 2013 10:41 pm
 
Forum: Genetics
Topic: mutation-selection balance
Replies: 0
Views: 3362

Theories - Origin of Life

... is dependent on the properties of both the mutation itself (its selection coefficient) and the population in which it arises (effective population size). These two things ...

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by Luxorien
Sat Mar 10, 2012 5:03 pm
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929587

Evolution Homework

I see where you are going now, I was hung on what the intensity of selection/coefficient of selection would be but I see that a recessive lethal allele is a special case. ...

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by kdeponte
Tue Oct 04, 2011 7:18 am
 
Forum: Evolution
Topic: Evolution Homework
Replies: 2
Views: 4417

Evolution Homework

... maybe I am over-thinking this a bit.. I keep thinking that I need the coefficient of selection but I'm unsure of how to figure that out.

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by kdeponte
Tue Oct 04, 2011 4:30 am
 
Forum: Evolution
Topic: Evolution Homework
Replies: 2
Views: 4417


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