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Selectin

Definition

noun, plural: selectins

Any of the large group of cell adhesion molecules described as carbohydrate-binding adhesion receptors


Supplement

Selectins are comprised of:

Selectins are found chiefly on the cell surface of white blood cells and mediate the binding of white blood cell to the endothelial cell, thus, are involved in host defense mechanisms, particularly the binding and rolling of the white blood cell to the endothelium.

The selectin family is comprised of three major groups:


Related term(s):

Reference(s):

  • Goodman SR. 2008. Cell Adhesion and the Extracellular Matrix. In: Medical Cell Biology. 3rd ed. London: Academic Press. p191-226.

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Immunohistochemistry HELP--paraffin vs frozen sections

... slide staining, and I'm having problems getting the staining to show correctly. So far, I've been staining lymph node tissue for CD62L (L-selectin) and CD3, both of which are supposed to be quite abundant on the surface of regular T cells in the lymph node (this is a control). First, I ...

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by wetheril
Fri Mar 30, 2007 8:48 pm
 
Forum: Molecular Biology
Topic: Immunohistochemistry HELP--paraffin vs frozen sections
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