It was first discovered by French scientist Henri Boulard at Southeast Asia in an effort to control the cholera and was related to Saccharomyces cerevisiae but dissimilar in metabolic and genetic properties.
Saccharomyces boulardii is non-pathogenic non-systemic that tend to stay in the gastrointestinal tract rather than scattering in the body. It also grows at high temperature of 37°C and shows antimicrobial effects in Escherichia coli and Salmonella typhimurium wherein these two strain of pathogenic bacteria usually associated with acute infectious diarrhea that revealed to adhere in mannose on the surface of Saccharomyces boulardii via lectin receptors, when the invading microbe is hurdle to Saccharomyces boulardii it is prohibited from connecting to the brush border thereby it is removed from the body during the next bowel movement.
Saccharomyces boulardii is used as gastrointestinal support in treating diarrhea including the infectious rotaviral in children, overgrowth the bad bacteria in gastrointestinal system, inflammatory bowel syndrome, irritable bowel syndrome, vaginal yeast infection, high cholesterol level and urinary tract infection.
• Saccharomyces cerevisiae
Species: Saccharomyces boulardii