Dictionary » S » Sabin-feldman dye test

Sabin-feldman dye test

Sabin-Feldman dye test

A method for the detection of anti-toxoplasma antibody in serum, based on the fact that toxoplasma gondii cells (from peritoneal exudate in mice) are fairly well stained with alkaline methylene blue, whereas organisms in a serum that contains specific antibody have no affinity for the dye; furthermore, normal toxoplasma cells become rounded, and the nucleus and cytoplasm deeply stained, when treated with the methylene blue; on the other hand, when dye is mixed with organisms and antibody, the cells retain their crescent shape and only the shrunken nuclear endosome is stained.

Please contribute to this project, if you have more information about this term feel free to edit this page

Results from our forum


... who do not agree that "Vivisection is a safer alternative to human testing.' Species difference makes it impossible for medicine for one species ... the disease or to treat those persons suffering from it." - Dr. A. Sabin, 1986, developer of the oral polio vaccine. "Everyone should ...

See entire post
by noratmedicineforme
Mon Mar 15, 2010 3:00 am
Forum: General Discussion
Topic: PETA
Replies: 54
Views: 44828

This page was last modified 21:16, 3 October 2005. This page has been accessed 8,296 times. 
What links here | Related changes | Permanent link