
Dictionary » R » Rough endoplasmic reticulum Rough endoplasmic reticulumrough endoplasmic reticulum noun (Abbreviation: RER) (Science: Cell biology) an endoplasmic reticulum (ER), a eukaryotic organelle made up of a system of membranous tubes and sacs, that is studded with ribosomes on its surface giving it a rough appearance under the microscope (hence its name). However, the ribosomes are not always bound with the ER. They bind to it when it starts to synthesize membrane-bound proteins destined for sorting. ![]()
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