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Robertsonian translocation

Robertsonian translocation

(Science: molecular biology) A special type of nonreciprocal translocation in chromosomes whereby the long arms of two nonhomologous acrocentric chromosomes are attached to a single centromere.

The short arms become attached to form a reciprocal structure that however often disappears some divisions after its formation.

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A question from Cloning

... different organisms have different numbers of chromosomes due to these robertsonian translocation mechanisms. And please, remember something else: we define a species by the virtue ...

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by MrMistery
Wed Oct 14, 2009 12:46 pm
Forum: Cell Biology
Topic: A question from Cloning
Replies: 26
Views: 27441

How does Head To Head Telomere Fusion express itself?

... cannot confirm how a "head to head telomeric fusion" (not a Robertsonian translocation) such as human chromosome 2 would express itself in the first generations. About ...

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by GaryGaulin
Sat Aug 22, 2009 3:40 am
Forum: Cell Biology
Topic: How does Head To Head Telomere Fusion express itself?
Replies: 5
Views: 12828

Regarding Mutation

... extra chromosome 21 material that causes Down syndrome may be due to a Robertsonian translocation in the karyotype of one of the parents. In this case, the long arm of chromosome ...

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by kolean
Sun Jul 12, 2009 8:37 pm
Forum: Genetics
Topic: Regarding Mutation
Replies: 5
Views: 6875

Karyotyping and Probing

i would try a FISH experiment. Since a Robertsonian translocation is a dicentric fusion and the acentric parts fragment will be lost, you should be able ...

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by sdekivit
Fri Jul 13, 2007 8:02 am
Forum: Genetics
Topic: Karyotyping and Probing
Replies: 1
Views: 1484

karyotyping and Probing

i have some uncertainty regarding robertsonian translocation. if i have only one cell, how am i able to do the karyotyping? i understand that the Robertsonian ...

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by aaroncjj_2020
Fri Jul 13, 2007 7:24 am
Forum: Molecular Biology
Topic: karyotyping and Probing
Replies: 0
Views: 884
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