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Abbreviation for ribonucleic acid: a nucleic acid that is generally single stranded (double stranded in some viruses) and plays a role in transferring information from DNA to protein-forming system of the cell.


Structure: Ribonucleic acid (RNA) is a molecule consisting of a long linear chain of nucleotides. Each nucleotide unit is comprised of a sugar, phosphate group and a nitrogenous base. It differs from a DNA molecule in a way that the sugar backbone is a ribose (deoxyribose in DNA) and the bases are adenine, guanine, cytosine and uracil (thymine in DNA).

Location: In eukaryotes, it is found in the nucleus and in the cytoplasm

Function: In some viruses, RNA is the genetic material. For most organisms, RNAs are involved in:

Compare: DNA

See also: nucleic acid

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Gel electrophoresis

yep, something like that. Maybe RNA, degradation? Who knows...

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by JackBean
Thu Mar 13, 2014 2:18 pm
Forum: Genetics
Topic: Gel electrophoresis
Replies: 3
Views: 382

Classification of non-coding RNA

We wish to share RNAcon, a web-server for the prediction and classification of non-coding RNAs. It uses SVM-based model for the discrimination between coding and ncRNAs and RandomForest-based prediction model for the classification of ncRNAs into different classes. The structural information based g...

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by raghavagps
Sat Feb 15, 2014 3:39 pm
Forum: Bioinformatics
Topic: Classification of non-coding RNA
Replies: 0
Views: 194

Re: Comprehensive List of long noncoding RNA(lncRNA) databases

This new database could be useful to many researchers interested in lncRNAs involved in respiratory infections caused by influenza and SARS-CoV viruses: (1) MONOCLdb , the MOuse NOnCode Lung database, a database for mouse long non-coding RNAs (lncRNA) involved in Influenza and SARS-CoV infections. w...

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by monocldb
Sat Feb 08, 2014 7:22 pm
Forum: Molecular Biology
Topic: Comprehensive List of long noncoding RNA(lncRNA) databases
Replies: 2
Views: 1648

Re: A dilution question about RNA

Why, for God's sake would you make a DNase treatment in 1ml??? :shock: You would take around 30 ul of your RNA (100ug / 3.3ug/ul), add the DNase worth few tens of bucks at least, 100 ul of 10x buffer and water up to 1 ml.

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by JackBean
Thu Feb 06, 2014 4:31 pm
Forum: Molecular Biology
Topic: A dilution question about RNA
Replies: 1
Views: 334

RNA integrity and RNA fragmentation?

After RNA isolation and before following experiments, I know that RNA quality so called RNA integrity is so important. So why there is a RNA fragmentation kit? Do we need RNA intact or fragmented?

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by golgicik
Mon Feb 03, 2014 9:15 pm
Forum: Molecular Biology
Topic: RNA integrity and RNA fragmentation?
Replies: 1
Views: 282
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