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Rhodopsin

rhodopsin

(Science: protein) light sensitive pigment formed from retinal linked through a Schiff's base to opsin: rhodopsin is an integral membrane protein found in the discs of retinal rods and cones, comprising some 40% of the membrane. Vertebrate opsins are proteins of 38 kD.

See: bacteriorhodopsin.


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Confusion: Rod cells,rhodopsin bleaching

I'm confused as to why,when exposed to bright light, rod cells cease to function. I understand that exposure to bright light bleaches all of the rhodopsin, but...so what? Why doesn't the bleached product (opsonin/retinal) simply get re-synthesised back into rhodopsin as it does in dim light, and ...

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by ADAS137
Sun Jan 01, 2012 10:26 pm
 
Forum: Human Biology
Topic: Confusion: Rod cells,rhodopsin bleaching
Replies: 0
Views: 919

Re: X Ray crystallography & transmembrane proteins

... proteins in toto is one of the “holy grails” of crystallography. There is no general way to do it and of the few cases that have succeeded, two (rhodopsin and F1-ATPase) won Nobel Prizes. Transmembrane regions of membrane and integral membrane proteins tend to be very hydrophobic. When you isolate ...

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by blcr11
Fri Sep 05, 2008 11:43 am
 
Forum: Molecular Biology
Topic: X Ray crystallography & transmembrane proteins
Replies: 5
Views: 5070

pharmaceutical discovery techniques

I'm not sure if i have posted this in the right section but here goes... I'm doing a project on rhodopsin which in part requires me to explain how the structural and functional aspects can be used for developing or discovering new pharmaceutical products. i have found loads ...

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by scott25
Sun Aug 17, 2008 12:21 pm
 
Forum: Molecular Biology
Topic: pharmaceutical discovery techniques
Replies: 2
Views: 1743

Uni Help: Need help on rhodopsin asap.

I have found out that the human retina has 3 rhodopsin transcripts sized 2.8,1.9 and 1.5kb. can someone tell me about the mechanism that produces these and what the functional significance might be??? Thx in advance

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by latkan2
Sun Oct 07, 2007 6:33 pm
 
Forum: Genetics
Topic: Uni Help: Need help on rhodopsin asap.
Replies: 3
Views: 1491

The Fiber Disease

... Juniper's Jewels and poplar's pearls are unseen treasures manifested in whorls. Nature's lattice glory, iridescent delight, with gleaming rhodopsin, the hue of midnight. Transcendental translucence, dioptrics by day, repeated refractions, transfusing the way. Perpetual prisms, crystals ...

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by codon blue
Sat Dec 23, 2006 11:46 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5560440
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