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Recombination

Definition

noun, plural: recombinations

(1) (genetics) The process or act of exchanges of genes between chromosomes, resulting in a different genetic combination and ultimately to the formation of unique gametes with chromosomes that are different from those in parents.

(2) (general) The process or act of bringing together (dissociated materials) once more.


Supplement

In genetics, recombination occurs during meiosis when chromosomes exchange genes. Thus, recombination is one of the important means to promote and increase genetic diversity between generations.


Word origin: re- (again) + combination

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How a gene detect where to insert after injected to nucleus

That depends whether you add some homology sequences and homology recombination will be used to incorporate that gene. Honestly, I don't know, what's the ratio of HR and NHEJ in human.

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by JackBean
Sun Feb 17, 2013 10:48 pm
 
Forum: General Discussion
Topic: How a gene detect where to insert after injected to nucleus
Replies: 1
Views: 260

Help??? Genetics problem cannot figure it out?

Genes for color blindness and hemophilia are linked on the X-chromosome in humans with a recombination frequency of 30%. A woman whose father was a color blind hemophiliac and mother was normal with no history of color blindness and hemophilia wants to have children. ...

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by adamk92
Sun Feb 17, 2013 10:29 pm
 
Forum: Genetics
Topic: Help??? Genetics problem cannot figure it out?
Replies: 2
Views: 223

Markerless mutants using suicide vector

Are you sure that the bacteria is capable of homology recombination? Is your vector linearized? What about usage of two linear pieces which are homologous to each other?

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by JackBean
Tue Dec 18, 2012 8:56 pm
 
Forum: Genetics
Topic: Markerless mutants using suicide vector
Replies: 2
Views: 531

λ Phase Genetic Switch

the λ-phage inserts his DNA by recombination; the integration is site-specific, the recognition-site is found to by 15bp long and is located between the gacactose and tryptophan genes... My thesis: as long as the plasmid DNA doesn`t contain ...

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by lenni
Thu Nov 01, 2012 10:08 am
 
Forum: Microbiology
Topic: λ Phase Genetic Switch
Replies: 1
Views: 501

How dominance works at the DNA/RNA/protein

... when each chromosome is duplicated and 2 sister chromatids are joined at the centromere. They would be identical to each other IF there was no recombination... The rest of your reasoning is faulty at best. I’ll try to explain with another example… Suppose you have two pea plants, one gives ...

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by Cat
Fri Oct 05, 2012 1:15 am
 
Forum: Genetics
Topic: How dominance works at the DNA/RNA/protein
Replies: 10
Views: 2050
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