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Receptors transferrin

receptors, transferrin

membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.


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Biology Calculation-is this correct?

Hey, for the number of transferrin receptors in each coated pit I've got: 100 000 receptors, 70% localised within the coated pits so: 100 000 ...

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by Kezzer
Thu Dec 02, 2010 10:19 pm
 
Forum: Molecular Biology
Topic: Biology Calculation-is this correct?
Replies: 5
Views: 3166

Re: Biology Calculation-is this correct?

... 68micrometers squared. The next question is to then calculate how many transferrin receptors there are in each coated pit, but I just can't get my head round how to do that.

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by Kezzer
Tue Nov 30, 2010 5:16 pm
 
Forum: Molecular Biology
Topic: Biology Calculation-is this correct?
Replies: 5
Views: 3166

Biology Calculation-is this correct?

... vesicle that will be formed from it. If the cell surface has 100,000 transferrin receptors, around 70% are localised within coated pits: work out how many coated pits there ...

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by Kezzer
Sun Nov 28, 2010 4:49 pm
 
Forum: Molecular Biology
Topic: Biology Calculation-is this correct?
Replies: 5
Views: 3166

Calculations

... out! Think I've got the answer to number 5 too. 5. There are 100,000 transferrin receptors, 200,000 are bound. We need equal concentrations of bound and unbound receptors, ...

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by hotlikefudge
Mon Dec 04, 2006 1:00 pm
 
Forum: Cell Biology
Topic: Calculations
Replies: 3
Views: 2780

Calculations

... answers, not sure if correct though: 3. Concentration in pits: 70,000 receptors (70% of 100,000) / 68 (2% of 3400- the surface area covered in ... * Avagadro (6.022 *10^15) =6.022 * 10^15 - 200,000 (molecules of Transferrin needed) =6.002 *10^15. Thats all I've done so far. Do you know ...

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by hotlikefudge
Sun Dec 03, 2006 11:41 pm
 
Forum: Cell Biology
Topic: Calculations
Replies: 3
Views: 2780
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