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Receptors insulin

receptors, insulin

cell surface proteins that bind insulin and trigger intracellular changes which influence the behaviour of cells. The best understood physiological consequence of insulin receptor activation is increased transport of glucose into most cells, which controls the rate of carbohydrate metabolism. The insulin receptor is a multifunctional protein complex that has intrinsic tyrosine kinase activity and is capable of autophosphorylation.


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Re: Campbell and Reece 8th edition

thank you quickly : "And BTW, the receptors do not have to be on the outside of the cell" don't you mean organelles ... able, after years of effort, to reconstruct the complete amino acid sequence of insulin. Since then, most of the steps involved in sequencing a polypeptide have ...

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by Stephen1993
Thu Apr 28, 2011 12:28 pm
 
Forum: Cell Biology
Topic: Campbell and Reece 8th edition
Replies: 36
Views: 26533

Pls. I need help with my hw

... GLUT4 transported on skeletal muscle occurs fast EXCEPT? A) When insulin is available B) During periods of hypoglycemia C) During the fed ... EXCEPT? A. Hormones B. Autocrines C. Neurotransmitters D. Neurohormones Receptors for some lipophilic ligands (non-polar ligands) are found in the ...

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by mslazy
Sat Oct 09, 2010 8:56 pm
 
Forum: Physiology
Topic: Pls. I need help with my hw
Replies: 1
Views: 11308

Insulin resitance

There's some debate on this, and the answer probably varies: fewer receptors, receptors variants that don't work as well, insulin variants that don't connect as well, processes getting in between production and connection, ...

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by Darby
Sun Apr 18, 2010 9:39 pm
 
Forum: Human Biology
Topic: Insulin resitance
Replies: 2
Views: 988

Diabetes

There are a few things wrong with the initial description - Insulin increases uptake in cells (but insulin does not bind directly to glucose, ... be affected. And I'm afraid that the stuff about mitochondria and insulin receptors makes no metabolic sense at all.

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by Darby
Mon Jan 04, 2010 11:35 pm
 
Forum: Human Biology
Topic: Diabetes
Replies: 2
Views: 1915

Diabetes

When food is digested, the sugars wind up in the blood stream. Insulin is a protein that can bind to the glucose molecules and to surface receptors on cells. When blood sugar spikes due to eating a meal or drinking something sweet, ...

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by Hodag
Sun Jan 03, 2010 2:01 pm
 
Forum: Human Biology
Topic: Diabetes
Replies: 2
Views: 1915
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