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Receptor site


noun, plural: receptor sites

A molecular site or the docking port on the surface of, or within, a cell, usually involving proteins that are capable of recognizing and binding with specific molecules.


For example: CD4 receptor on the surface of certain cells is the receptor site that HIV binds with and uses to enter cells.

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cAMP 2nd Messenger Pathway and Experiments

... still produced in experiment 2? ---There could be an issue with the receptor that comes before adenylyl cyclase, so ATP is unable to be converted ... affinity for the hormone receptor. It interacts with GTP regulatory site to prohibit the GDP from binding. If ATP or GTP were eliminated from ...

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by mkay28
Tue Sep 24, 2013 10:43 pm
Forum: Cell Biology
Topic: cAMP 2nd Messenger Pathway and Experiments
Replies: 2
Views: 3557

Re: O level Past paper exam question on gland secretion

... it will need to reach a minimum threshold or exceed that threshold of receptor-molecule complexes in order to produce a response, small physical ... to be excessively big as long as they can attach to the specific active site. I hope this all helps, as I said, I am no expert in this field these ...

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by Amphibitile
Sun Jun 23, 2013 12:37 am
Forum: General Discussion
Topic: O level Past paper exam question on gland secretion
Replies: 1
Views: 3130

cellular mechanisms that result in symptoms of cholera

... B subunit ring. Upon binding, the complex is taken into the cell via receptor-mediated endocytosis. Once inside the cell, the disulfide bond is ... ADP-ribosylation factor 6 (Arf6). [13] Binding exposes its active site, allowing it to permanently ribosylate the Gs alpha subunit of the heterotrimeric ...

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by adithya528
Tue Dec 11, 2012 1:49 pm
Forum: Cell Biology
Topic: cellular mechanisms that result in symptoms of cholera
Replies: 4
Views: 7190

Re: Muscle Contractions

... into the neuromuscular junction... Once the Ach binds to its nicotinic receptor, it opens ligand gated channels for Na+ diffusion into muscular ... change thus moving tropomyosin allowing the myosin binding site to become open. These binding sites form a cross bridge with actin with ...

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by Jpoley
Tue Mar 01, 2011 2:42 am
Forum: Human Biology
Topic: Muscle Contractions
Replies: 1
Views: 7860

Competitive receptor-ligand Binding

... has posted a few statements in his lecture pertaining to what he calls 'receptorology' and I'm just trying to elaborate a bit on them in lieu of ... only conclusion I could think of is that there could be another binding site (one of lower affinity) which would increase the maximal response, any ...

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by someguy456345
Thu Feb 24, 2011 7:48 pm
Forum: Cell Biology
Topic: Competitive receptor-ligand Binding
Replies: 0
Views: 2159
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