Dictionary » Q » Quinine

Quinine

Definition

noun

(pharmacology) A bitter, crystalline, alkaloid powder extracted from Cinchona bark used for medical purposes such as for the treatment of malarial disease


Supplement

Quinine is a crystalline alkaloid that is bitter in taste, whitish in color (or colorless), and needle-like in shape. Its IUPAC name is (R) - (6 – Methoxyquinolin – 4 - yl) ((2S, 4S, 8R) – 8 –vinylquinuclidin – 2 - yl) methanol. It is obtained from cinchona bark. At present, it has been synthesized in the laboratory. The medicinal property of the cinchona plant is traced back to the indigenous people of Peru and Bolivia.

Quinine is used as an alternative treatment for certain malarial diseases, particularly those that are resistant to pharmacological treatments. It was first found to be effective against Plasmodium falciparum in the 17th century. It used to be the drug of choice in treating malaria until chloroquine drug became available and preferred in the 1940s due to the latter's efficacy and fewer side effects.

Apart from antimalarial treatment, quinine was also used to treat lupus and arthritis. It has an analgesic (painkilling), anti-inflammatory, antipyretic, and cardiac depressant effects. It also reduces the excitability of the motor end plate. It is used as an ingredient of tonic water.


Word origin: Spanish quina (bark) + -ine

See also:


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re: UV Reflective Staining

... acetate is another - both glow under UV light). Anyway, other potential candidates include phosphorus (which glows white under UV light) and quinine .

See entire post
by JoshuaFlynn
Mon May 07, 2012 11:28 am
 
Forum: Human Biology
Topic: UV Reflective Staining
Replies: 9
Views: 8424

The Fiber Disease

... pelletierine. Pyrrolidine group: hygrine, cuscohygrine, nicotine Tropane group: atropine, cocaine, ecgonine, scopolamine Quinoline group: quinine, quinidine, dihydroquinine, dihydroquinidine, strychnine, brucine, veratrine, cevadine Isoquinoline group: The opium alkaloids (morphine, codeine, ...

See entire post
by Skytroll
Wed Jul 12, 2006 6:01 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6066856

Outline for Malaria powerpoint on Ecology and transmission

... even go farther: start by the description of the disease (same as TB), it's cause, symptoms, treatments, prevention, resistance to treatments (quinine, artemisine) and to insecticides. That is also where you will give the You could place the sickle cell anemia in this part (Andrew is right, ...

See entire post
by canalon
Sat Sep 24, 2005 11:09 pm
 
Forum: Microbiology
Topic: Outline for Malaria powerpoint on Ecology and transmission
Replies: 13
Views: 10811


This page was last modified 05:38, 1 February 2015. This page has been accessed 4,054 times. 
What links here | Related changes | Permanent link