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Pyruvate

Definition

noun

The carboxylate anion of pyruvic acid.


Supplement

Pyruvate is the end product of glycolysis, which is converted into acetyl coA that enters the Krebs cycle when there is sufficient oxygen available. When the oxygen is insufficient, pyruvate is broken down anaerobically, creating lactate in animals (including humans) and ethanol in plants.


Word origin: PYR(O)– + Latin ūva, grape (from its being produced by the dry distillation of racemic acid, originally derived from grapes) + -ate.

Related forms: pyruvic (adjective).
Related phrases: phosphoenol pyruvate, pyruvate decarboxylation.

See also: pyruvic acid, cellular respiration, glycolysis.


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Results from our forum


Re: Food to ATP energy?

... yield) be converted into about 30 moles of ATP. Many biology textbooks will state 38, but they do not account for the cost of transporting pyruvate and ADP into the mitochondria, and other costs to move molecules for the entire process. There are ~4 kilocalories, our ~4 Calories (with a ...

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by tmbirkhead
Thu Aug 14, 2014 1:11 am
 
Forum: Cell Biology
Topic: Food to ATP energy?
Replies: 2
Views: 1693

Re:

well, since they give only round hundreds, they are not interested in partiall pathways (like if half of the pyruvate was degraded before it was stopped due to lack of NAD+ and FAD:) Glycolysis will definitelly take part. Probably also the pyruvate decarboxylation. However, the ...

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by caters
Mon Feb 03, 2014 4:37 am
 
Forum: Cell Biology
Topic: ATP produced by human cells in an anaerobic chamber. LOST!
Replies: 2
Views: 4307

Re:

... check at another textbook and you were right! Unlike what I first thought, glycolysis can't take place once glycogenolysis has started because the pyruvate kinase is inhibited by glucagon and adrenaline, so PEP can't turn into pyruvate anymore. Which is only adding to my confusion...

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by Aymeric
Sat Dec 14, 2013 11:51 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6257

Re: When does gluconeogenesis kick in during physical activity?

... and transported to peripheral tissues where is it utilised. And it uses alanine as the solely amino acid, because it's freely exchangeable with pyruvate and lactate.

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by JackBean
Fri Dec 13, 2013 12:14 pm
 
Forum: Human Biology
Topic: When does gluconeogenesis kick in during physical activity?
Replies: 12
Views: 6257

ATP produced by human cells in an anaerobic chamber. LOST!

well, since they give only round hundreds, they are not interested in partiall pathways (like if half of the pyruvate was degraded before it was stopped due to lack of NAD+ and FAD:) Glycolysis will definitelly take part. Probably also the pyruvate decarboxylation. However, the ...

See entire post
by JackBean
Wed Nov 06, 2013 8:18 am
 
Forum: Cell Biology
Topic: ATP produced by human cells in an anaerobic chamber. LOST!
Replies: 2
Views: 4307
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