Dictionary » P » Putative




Denoting a supposition or inference based on what was commonly believed, reputed, or deemed rather than on a direct evidence


The word putative is used to describe an entity or a concept that is based on what is generally accepted or inferred even without a direct proof of it.

Putative gene, for instance, refers to a nucleotide sequence believed to be a gene because of its open reading frame although its function and the protein it codes for has not been (fully) identified.1 For example, Putative gene 57 is the (temporary) name suggested for the gene coding for a protein produced by Bacteriophage SP01 that infects the bacterium, Bacillus subtilis.2

Other examples:

  • Putative 32-kDa heart protein
  • Putative ADAM18 Gene Product
  • Putative alpha-synuclein-binding protein
  • putative chemokine receptor
  • putative claudin-24
  • putative DNA/chromatin binding motif 2
  • Putative eukaryotic translation initiation factor 1A
  • Putative folate hydrolase 1B
  • putative G protein-coupled receptor
  • putative golgin subfamily A member 6B

Word origin: Middle French putatif, from Latin putātīvus (supposed, purported), from putātus (thought), from putō.

Mentioned in:

1Slonczewski, Joan; John Watkins Foster (2009). Microbiology: An Evolving Science. New York: W.W. Norton & Co.
2Stewart CR, Gaslightwala I, Hinata K, Krolikowski KA, Needleman DS, Peng AS, Peterman MA, Tobias A, Wei P. Genes and regulatory sites of the "host-takeover module" in the terminal redundancy of Bacillus subtilis bacteriophage SPO1. Virology. 1998 Jul 5; 246 (2): 329-40.

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Results from our forum


... possibility is that there has been one or more mutation(s) in one of the primer binding sites so that the primer has some mispairs with its putative target and the affinity of the primer for the altered target is below the affinity needed for efficient PCR.

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by jonmoulton
Tue Jan 29, 2013 4:16 pm
Forum: Genetics
Topic: PCR
Replies: 2
Views: 3614

Re: Are evolution and creationism mutually exclusive???

... in a living thing over time' as 'evolution'. There has been speciation, genetic drift, etc but again, these mechanisms have NOTHING to do with the putative origin of a genome, from non living matter, through natural processes, which then gets more and more complex over time, for no reason other ...

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by jinx25
Mon Oct 08, 2012 1:19 am
Forum: Evolution
Topic: Are evolution and creationism mutually exclusive???
Replies: 24
Views: 18766

Nucleotide Database

... to find some apetala gene sequence. However, what you will probably end up with will be DNA library and degenerated probe, which will lead you to putative apetala gene from Hibiscus. After sequencing and further characterization you should be able to say how related it is to known apetala genes ...

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by JackBean
Tue Sep 25, 2012 9:19 am
Forum: Molecular Biology
Topic: Nucleotide Database
Replies: 9
Views: 4627

Nucleotide Database

... However, unless you have a mutant that you can use to prove your gene IS apetala, your work would be insufficient as everything would be "putative".

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by Cat
Wed Sep 19, 2012 3:40 pm
Forum: Molecular Biology
Topic: Nucleotide Database
Replies: 9
Views: 4627

Re: T7 Expression System

... The use of blue-sephadex, Ap5A elution and a second G-100 sephadex separation yield homogenous adenylate kinase in E.Coli anyway (the putative gene i'm dealing with show's a high degree of similarity in sequence to E.Coli AK). However this would not solve the problem of the endogenous ...

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by TjCooper
Tue Jan 03, 2012 1:22 pm
Forum: Molecular Biology
Topic: T7 Expression System
Replies: 5
Views: 4219
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