Proton pump inhibitor
proton pump inhibitor
(Science: pharmacology) A group of anti-ulcer medications which work by binding to H_/K_ aTPase, an enzyme which is found on the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with potasium) into the gastric lumen.
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... HCL at a concentration of 0.1M. The secreted -protons, which are derived from the intracellular hydration of CO2 by carbonic anhydrase, are pumped out by an (H+ k+) ATPase antiport transporter ... secretion of HCL. d) Explain how a proton pump inhibitor might be effective in the treatment of ...
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