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Proteoglycan

proteoglycan

(Science: protein) A high molecular weight complex of protein and polysaccharide, characteristic of structural tissues of vertebrates, such as bone and cartilage, but also present on cell surfaces. Important in determining viscoelastic properties of joints and other structures subject to mechanical deformation. Glycosaminoglycans (gAGs), the polysaccharide units in proteoglycans, are polymers of acidic disaccharides containing derivatives of the amino sugars glucosamine or galactosamine.


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The importance of hyaluron acid in cartillage

... the function is to 'catch' water in the cartillage. Cartillage is a tissue that is resistent to compressing pressure. ---> hyaluronic acid is a proteoglycan that is very hydrophilic and thus attacheswater: the cartillage tissue will swell and thus will be resitent to compressing. Also, as you ...

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by sdekivit
Sat Jan 13, 2007 7:19 pm
 
Forum: Cell Biology
Topic: The importance of hyaluron acid in cartillage
Replies: 2
Views: 2361

The Fiber Disease

... of proteinases in body fluids of humans and animals." TACTICS "?superoxide production by the stimulation with opsonized zymosan, proteoglycan cell wall remained reduced. Corresponding to the reduction in superoxide-producing activity, the killing activity also remained reduced. ...

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by Nadas Moksha
Tue Aug 29, 2006 9:36 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988302

The Fiber Disease

... Proteins could be fibers, filaments, nanowires? From outer space? article on MS from Medscape: Chronic barium intoxication disrupts sulphated proteoglycan synthesis: a hypothesis for the origins of multiple sclerosis. High level contamination by natural and industrial sources of the alkali ...

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by Skytroll
Fri Aug 11, 2006 4:28 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 4988302

What's the difference between proteoglycans and cartilage?

Proteoglycan is a chemical substance.... It is indeed found in high concentration in cartilages... It's like comparing water to the ocean

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by MrMistery
Wed Jun 29, 2005 7:54 pm
 
Forum: Cell Biology
Topic: What's the difference between proteoglycans and cartilage?
Replies: 1
Views: 2125


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