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Protein kinase c

protein kinase c

(Science: enzyme) An enzyme that phosphorylates proteins on serine or threonine residues in the presence of physiological concentrations of calcium and membrane phospholipids. The additional presence of diacylglycerols markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by phorbol esters and it is believed that protein kinase c is the receptor protein of tumour-promoting phorbol esters.

Registry number: EC 2.7.1.-


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Cell signalling inhibitors

... me the enzyme or receptor that is inhibited? (Preferably for tyrosine kinase, G-protein, JAK/STAT and Phosphatidylinositol 3-kinase) Thanks :D

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by billyfisher100
Wed Jan 08, 2014 7:35 pm
 
Forum: Cell Biology
Topic: Cell signalling inhibitors
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Views: 1531

Questions on the Sodium Potassium Pump and Enzymes

... cycle there is a phosphate group being added and taken away from the protein so surely kinase and phosphotase are involved because an ATPase only hydrolyses ATP? Also, we are just ...

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by JoWillyTso
Mon Nov 05, 2012 5:50 pm
 
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Topic: Questions on the Sodium Potassium Pump and Enzymes
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... response in adipose tissue as shown by attenuated glucose-regulated protein 78/C/EBP homologous protein (CHOP) protein abundance and c-Jun NH2-terminal kinase activation. Our findings suggest that betaine might serve as a safe and efficacious ...

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by jinx25
Mon Oct 08, 2012 2:54 am
 
Forum: General Discussion
Topic: Beet Root Pigment
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Views: 3674

Re: Kinases

... in the molecule. If the terminal phosphate of ATP is transferred to a protein (releasing free ADP) then the system is in a lower-energy state that ... drive the reaction to the ADP & phosphoprotein side. Not every kinase will use ATP as a substrate. Other high-energy phosphates are available ...

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by jonmoulton
Mon Sep 24, 2012 3:13 pm
 
Forum: Cell Biology
Topic: Kinases
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Views: 1896

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... called compartments. Specific reduction of dAkt" ( Drosophila Akt protein kinase) "function, an essential component of the insulin signaling pathway, in either ...

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by animus
Thu Jun 28, 2012 4:41 pm
 
Forum: Human Biology
Topic: organs shape
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