Dictionary » P » Protein domain

Protein domain

Definition

noun

(1) An autonomously folding functional unit of a protein.

(2) A part of protein that can fold, function and exist independently of the rest of the protein chain or structure.


Supplement

Protein domains vary in length. Some can consist of about 25 amino acids while others up to 500 amino acids in length. Zinc fingers are an example of small protein domains that can coordinate one or more zinc ions to help stabilize their folds.


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RNA

... of RNA pol which are the roles of the phosphorylaton of C terminal Domain of RNA polymerase? (more than one may apply) 1. It increases the speed ... not be consequences of RNA splicing 1. Insertion of amino acids in the protein sequence 2. Deletion of amino acids in the protein sequence 3. Substitution ...

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by 2468
Tue Nov 20, 2012 6:03 pm
 
Forum: Molecular Biology
Topic: RNA
Replies: 2
Views: 711

I have a problem seeing the bigger picture of research

... species? How about a smaller piece of the gene, eg. a specific protein domain, whether it rescues the phenotype? The idea of these approaches is to relate DNA to ...

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by FlyMusings
Sat Sep 29, 2012 5:14 pm
 
Forum: General Discussion
Topic: I have a problem seeing the bigger picture of research
Replies: 2
Views: 596

Connection between opioid receptors and fatty acid receptors

of course only the protein/gene, not whole genome :roll: But if you have 20% similarity over whole protein with several domains, that's nothing. If you've had at least 20% concentrated in one domain, then you could make some ...

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by JackBean
Fri Jul 27, 2012 1:32 pm
 
Forum: Evolution
Topic: Connection between opioid receptors and fatty acid receptors
Replies: 4
Views: 3934

Re:

Depends what part was similar. Was it only one domain? Was these 20% spread throughout whole sequence? Usually several parts but if blast finds similarity with 1 protein then it shows spread out overlap within that protein not over entire genome.

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by mhein
Wed Jul 25, 2012 7:17 pm
 
Forum: Evolution
Topic: Connection between opioid receptors and fatty acid receptors
Replies: 4
Views: 3934

Amyloid beta (A4) precursor protein degradation products

Amyloid beta (A4) precursor protein degradation products of the pathogenic role of Alzheimer's disease research ... component of senile plaques) and a variety of sizes ranging from APP intracellular domain (AICD). The traditional view is that the APP degradation by two ways. Α-secretase ...

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by Anonymous
Tue Jun 12, 2012 3:11 am
 
Forum: General Discussion
Topic: Amyloid beta (A4) precursor protein degradation products
Replies: 1
Views: 3096
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