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Protein a

protein A

protein obtained from staphylococcus aureus that binds immunoglobulin molecules without interfering with their binding to antigen. Widely used in purification of immunoglobulins and in antigen detection, for example by immunoprecipitation. A very effective b-cell mitogen.


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Ebola Virus: Development of Vaccines and Therapeutic Drugs

... for Ebola that contains an attenuated live virus, vesicular stomatitis virus (VSV), a common livestock pathogen, into which an Ebola viral coat protein has been introduced. With funding from the US DOD’s Defense Threat Reduction Agency (DTRA), Newlink Genetics Corp has licensed an Ebola vaccine ...

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by lorrainegenscript
Fri Aug 22, 2014 6:54 am
 
Forum: Molecular Biology
Topic: Ebola Virus: Development of Vaccines and Therapeutic Drugs
Replies: 0
Views: 28

The most boring tasks in Biology

... Posting multiple answers is fine. A few prerequisites: - It has to have to do with biological data (microscopic pictures, enzyme activities, protein structures…) - It has to be something that computers are not very good at doing If you are not sure about the prerequisites, don’t worry about ...

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by Emmezali
Fri Aug 15, 2014 2:41 pm
 
Forum: General Discussion
Topic: The most boring tasks in Biology
Replies: 1
Views: 278

Re: Totipotent Stem Cell From Molecular Components

I am not saying # of protein x = # of protein y(In fact this is almost never the case). Rather I am saying that for a particular protein in my stem cell at least, the amount of that particular protein is the average of the gene expression ...

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by caters
Fri Aug 01, 2014 1:42 am
 
Forum: Cell Biology
Topic: Totipotent Stem Cell From Molecular Components
Replies: 2
Views: 2367

Re: What does "deficient trafficking" means

... with: "not enough transport to the...". Without reading the paper I can't be sure of this. Based on your post, it sounds like the protein if interest is usually sent to the lysosome, but because it is misfolded it is tagged with a ubiquitin which leads to its degradation in the ...

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by jonmoulton
Wed Jul 02, 2014 2:38 pm
 
Forum: Cell Biology
Topic: What does "deficient trafficking" means
Replies: 1
Views: 422

What does "deficient trafficking" means

I was reading a paper on disease mechanism where misfolding of a particular protein leads to its degradation by ubiquitin proteasome pathway and deficient trafficking to the lysosome. What does deficient trafficking means and overall what does this sentence means?? ...

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by KSJ
Wed Jul 02, 2014 3:10 am
 
Forum: Cell Biology
Topic: What does "deficient trafficking" means
Replies: 1
Views: 422
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