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Prostaglandin e2

prostaglandin E2 --> dinoprostone

(Science: chemical) 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid. The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.

Pharmacological action: oxytocics.

Chemical name: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11alpha,13E,15S)-

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Cardiovascular disease (CVD)

... platelets stick to the roughened surface and release clotting factors called thromboxanes. In healthy arteries the amount of thromboxane and prostaglandin is balanced, but in damaged arteries the balance is upset because the endothelial cells lining the artery are damaged so blood clots form. ...

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by sharleenreyna
Wed Apr 20, 2011 9:48 am
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by svmichaela
Wed Oct 20, 2010 11:50 am
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by ezther
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by jasonfahy
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prostaglandin synthesis occurs locally, where the pain occurs. google for "paracrine hormone" to find out more. Aspirin inhibits the syntehsis everywhere cause it travels through the blood

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by MrMistery
Mon Mar 10, 2008 6:48 pm
Forum: Cell Biology
Topic: Painkillers
Replies: 5
Views: 4089
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