Prophase I



The first stage in the first meiotic division of meiosis. This stage is characterized by having five sub-stages namely leptotene, zygotene, pachytene, diplotene and diakinesis. It highlights the exchange of DNA between homologous chromosomes via a process called homologous recombination and the cross-over at chiasma(ta) between non-sister chromatids. Thus, this stage is important to increase genetic variation. This stage then ends with the disintegration of the nucleolus and the nuclear membrane.


Since meiosis consists of two consecutive nuclear divisions, prophase occurs twice. Thus, there are prophase I and prophase II.

See also: prophase II, meiosis I

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